{"id":519,"date":"2016-11-16T12:22:56","date_gmt":"2016-11-16T11:22:56","guid":{"rendered":"https:\/\/nugenis.eu\/?page_id=519&#038;lang=en"},"modified":"2025-02-13T15:01:12","modified_gmt":"2025-02-13T14:01:12","slug":"cartilage-protector","status":"publish","type":"page","link":"https:\/\/nugenis.eu\/en\/cartilage-protector\/","title":{"rendered":"Cartilage Protector"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-9wiy9r-7e5a4f79c16aa7cfe8aef38f9fd34507\">\n.avia-section.av-9wiy9r-7e5a4f79c16aa7cfe8aef38f9fd34507{\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/nugenis_home_10.jpg);\nbackground-position:0% 0%;\nbackground-attachment:scroll;\n}\n.avia-section.av-9wiy9r-7e5a4f79c16aa7cfe8aef38f9fd34507 .av-section-color-overlay{\nopacity:0.5;\nbackground-color:#000000;\nbackground-image:url(https:\/\/nugenis.eu\/wp-content\/themes\/nugenis\/images\/background-images\/grain_top.png);\nbackground-repeat:repeat;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-9wiy9r-7e5a4f79c16aa7cfe8aef38f9fd34507 main_color avia-section-default avia-no-shadow  avia-builder-el-0  el_before_av_section  avia-builder-el-first  avia-full-stretch avia-bg-style-scroll av-section-color-overlay-active av-minimum-height av-minimum-height-25 av-height-25  container_wrap sidebar_right'  data-section-bg-repeat='stretch' data-av_minimum_height_pc='25' data-av_min_height_opt='25'><div class=\"av-section-color-overlay-wrap\"><div class=\"av-section-color-overlay\"><\/div><a href='#next-section' title='' class='scroll-down-link  avia-svg-icon avia-font-svg_entypo-fontello' data-av_svg_icon='down-open-mini' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"15\" height=\"32\" viewBox=\"0 0 15 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-1' aria-describedby='av-svg-desc-1' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-1'>Scroll to next section<\/title>\n<desc id='av-svg-desc-1'>Scroll to next section<\/desc>\n<path d=\"M12.96 12.16q0.704-0.832 1.536 0 0.832 0.704 0 1.536l-6.272 6.144q-0.704 0.704-1.536 0l-6.272-6.144q-0.832-0.832 0-1.536 0.768-0.768 1.6 0l5.44 4.992z\"><\/path>\n<\/svg><\/a><div class='container av-section-cont-open' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-519'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-9p25kn-abefc0c1032e115dea1c5c87ec8696f8\">\n#top .av-special-heading.av-9p25kn-abefc0c1032e115dea1c5c87ec8696f8{\npadding-bottom:10px;\ncolor:#ffffff;\n}\nbody .av-special-heading.av-9p25kn-abefc0c1032e115dea1c5c87ec8696f8 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-9p25kn-abefc0c1032e115dea1c5c87ec8696f8 .special-heading-inner-border{\nborder-color:#ffffff;\n}\n.av-special-heading.av-9p25kn-abefc0c1032e115dea1c5c87ec8696f8 .av-subheading{\nfont-size:20px;\n}\n<\/style>\n<div  class='av-special-heading av-9p25kn-abefc0c1032e115dea1c5c87ec8696f8 av-special-heading-h1 custom-color-heading blockquote modern-quote modern-centered  avia-builder-el-1  el_before_av_hr  avia-builder-el-first '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >Epigenetic Cartilage Protector<\/h1><div class='av_custom_color av-subheading av-subheading_below'><p>Epigenetics Protects Our Joints<\/p>\n<\/div><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<div  class='hr av-9hxqv3-9f354c0c5c2626e9b0e81182d7da4252 hr-short  avia-builder-el-2  el_after_av_heading  avia-builder-el-last  hr-center'><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<\/div><\/div><\/main><!-- close content main element --><\/div><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-9bpdpb-63102a7694cb9306e762d6016a2073ee\">\n.avia-section.av-9bpdpb-63102a7694cb9306e762d6016a2073ee{\nbackground-color:#ffffff;\nbackground-image:unset;\n}\n<\/style>\n<div id='av_section_2'  class='avia-section av-9bpdpb-63102a7694cb9306e762d6016a2073ee main_color avia-section-default avia-no-border-styling  avia-builder-el-3  el_after_av_section  el_before_av_section  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-519'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-9670hz-40bca651b07d4378ae2707ea3bbf7e0a\">\n.flex_column.av-9670hz-40bca651b07d4378ae2707ea3bbf7e0a{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-9670hz-40bca651b07d4378ae2707ea3bbf7e0a av_three_fifth  avia-builder-el-4  el_before_av_two_fifth  avia-builder-el-first  first flex_column_div av-animated-generic left-to-right av-zero-column-padding  '     ><section  class='av_textblock_section av-8zzodj-461ed779c84243c1fd0a6063f9e3b63e '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p data-start=\"0\" data-end=\"22\"><strong data-start=\"0\" data-end=\"22\">Short Description:<\/strong><\/p>\n<p data-start=\"24\" data-end=\"774\"><strong>ECP\u00ae &#8211; Epigenetic Cartilage Protector<\/strong> is an innovative dietary supplement based on the principles of applied epigenetics. It contains the biologically active form of S-Adenosyl-L-Methionine (SAM-e), which is combined in a gastro-resistant capsule form with important vitamins and trace elements to protect and regenerate joint cartilage and intervertebral discs. SAM-e has anti-inflammatory, pain-relieving properties and promotes cell regeneration, particularly in degenerative joint conditions like osteoarthritis. It also supports the biosynthesis of spermidine, which has a chondroprotective effect. ECP\u00ae thus contributes to the improvement of joint function and structure, while protecting against cartilage and intervertebral disc degeneration.<\/p>\n<h1 style=\"text-align: center;\" data-start=\"776\" data-end=\"817\"><strong data-start=\"776\" data-end=\"817\">ECP\u00ae &#8211; Epigenetic Cartilage Protector<\/strong><\/h1>\n<p data-start=\"819\" data-end=\"1115\">A dietary supplement based on applied epigenetics with the highest possible proportion of the biologically active form of S-Adenosyl-L-Methionine as a coated granulate, along with the vitamins and trace elements essential for its biosynthesis, in a preventive dosage in gastro-resistant capsules.<\/p>\n<p data-start=\"1117\" data-end=\"1246\">The epigenetic mechanism of DNA methylation has a protective and regenerative effect on joint cartilage and intervertebral discs.<\/p>\n<p data-start=\"1248\" data-end=\"1301\"><strong data-start=\"1248\" data-end=\"1301\">S-Adenosylmethionine (SAM-e, Ademetionine) in ECP<\/strong><\/p>\n<p data-start=\"1303\" data-end=\"1602\">S-Adenosylmethionine (SAM-e, Ademetionine) has proven anti-inflammatory, pain-relieving, and tissue-promoting properties, especially useful for joint complaints such as osteoarthritis, which causes joint pain and reduced joint function [Jacobsen et al., 1991; Di Padova, 1987; Harmand et al., 1987].<\/p>\n<p data-start=\"1604\" data-end=\"1641\"><strong data-start=\"1604\" data-end=\"1641\">Structure of S-Adenosylmethionine<\/strong><\/p>\n<p data-start=\"1643\" data-end=\"1887\">The chemical structure of S-Adenosylmethionine was first described by Cantoni in 1952 (Cantoni, 1952), but a commercially viable parenteral product, a stabilized p-toluenesulfonate derivative, was only available in Italy in 1974 (Chavez, 2000).<\/p>\n<p data-start=\"1889\" data-end=\"2107\">S-Adenosylmethionine is derived from the sulfur-containing amino acid methionine and adenosine triphosphate (ATP) in the presence of Mg++, Co++, Mn++, and acts in the body on a variety of critical biochemical pathways.<\/p>\n<p data-start=\"2109\" data-end=\"2121\"><strong data-start=\"2109\" data-end=\"2121\">Sources:<\/strong><\/p>\n<p data-start=\"2123\" data-end=\"2280\">Cantoni C. J. 1952. S-adenosyl-1-methionine: a new intermediate formed enzymatically from L-methionine and adenosine triphosphate. J Am Chem Soc.; 74: 29\u201342.<\/p>\n<p data-start=\"2282\" data-end=\"2365\">Chavez, M. 2000. SAMe: S-Adenosylmethionine. Am. J. Health Syst. Pharm. 57: 119\u2013123<\/p>\n<p data-start=\"2367\" data-end=\"2456\">S-Adenosylmethionine (SAM, Ademetionine) is the sole methyl group donor for the DNA code.<\/p>\n<p data-start=\"2458\" data-end=\"2710\">Methionine adenosyltransferase (MAT) is responsible for synthesizing S-Adenosylmethionine from methionine and ATP, maintaining methylation in somatic tissue, and ensuring the normal development of an organism, making it indispensable for cell survival.<\/p>\n<p data-start=\"2712\" data-end=\"2792\">S-Adenosylmethionine is essential for three main metabolic pathways in the cell:<\/p>\n<ol data-start=\"2794\" data-end=\"3241\">\n<li data-start=\"2794\" data-end=\"3026\">\n<p data-start=\"2797\" data-end=\"3026\"><strong data-start=\"2797\" data-end=\"2821\">For transmethylation<\/strong>, where methyl groups (-CH3) from S-Adenosylmethionine are reversibly attached to the 5&#8242; position on the cytosine ring of DNA genetic information, temporarily silencing genes without altering the DNA code.<\/p>\n<\/li>\n<li data-start=\"3028\" data-end=\"3167\">\n<p data-start=\"3031\" data-end=\"3167\"><strong data-start=\"3031\" data-end=\"3055\">For transsulfuration<\/strong>, leading to the synthesis of glutathione, the most potent antioxidant protecting against oxidative cell damage.<\/p>\n<\/li>\n<li data-start=\"3169\" data-end=\"3241\">\n<p data-start=\"3172\" data-end=\"3241\"><strong data-start=\"3172\" data-end=\"3215\">Biosynthesis of spermidine and spermine<\/strong> through aminopropylation.<\/p>\n<\/li>\n<\/ol>\n<p data-start=\"3243\" data-end=\"3393\">Therefore, S-Adenosylmethionine is a central regulator of cell metabolism, influencing cell proliferation, differentiation, apoptosis, and cell death.<\/p>\n<p data-start=\"3395\" data-end=\"3468\"><strong data-start=\"3395\" data-end=\"3468\">S-Adenosylmethionine Stimulates Cartilage Formation in Osteoarthritis<\/strong><\/p>\n<p data-start=\"3470\" data-end=\"3968\">In osteoarthritis, molecular-level matrix-degrading enzymes, cytokines, and growth factors contribute to the destruction of collagen in the cartilage surface. Chondrocytes, the cartilage-forming cells, respond to this defect by increasing new cartilage formation, though this new cartilage is less resilient than the original. Over time, the cartilage surface becomes rougher, thinner, and cracked. Eventually, enough cartilage is lost that the joint bones begin to rub directly against each other.<\/p>\n<p data-start=\"3970\" data-end=\"4190\">The worn-down cartilage material enters the joint fluid and irritates the synovial membrane (as shown in the image), which can trigger a temporary inflammatory response in the synovial membrane: activated osteoarthritis.<\/p>\n<p data-start=\"4192\" data-end=\"4204\"><strong data-start=\"4192\" data-end=\"4204\">Sources:<\/strong><\/p>\n<p data-start=\"4206\" data-end=\"4456\">Annette Immel-Sehr. Osteoarthritis \u2013 Cartilage and Bone in Distress <a href=\"https:\/\/www.pharmazeutische-zeitung.de\/ausgabe-052018\/knorpel-und-knochen-in-bedraengnis\/\" target=\"_new\" rel=\"noopener\" data-start=\"4274\" data-end=\"4456\">https:\/\/www.pharmazeutische-zeitung.de\/ausgabe-052018\/knorpel-und-knochen-in-bedraengnis\/<\/a><\/p>\n<p data-start=\"4458\" data-end=\"4546\"><strong data-start=\"4458\" data-end=\"4546\">S-Adenosylmethionine (SAM, Ademetionine) is a Necessary Part of SPERMIDINE Synthesis<\/strong><\/p>\n<p data-start=\"4548\" data-end=\"4972\">Experimental studies show that Ademetionine (S-Adenosylmethionine) increases chondrocyte proteoglycan synthesis and their proliferation rate. It induces spermidine synthesis, which stabilizes the polyanionic macromolecules of proteoglycans and protects them from proteolytic and glycolytic enzyme attacks. Ademetionine (S-Adenosylmethionine) restores baseline conditions in synovial cells after cytokine-induced cell damage.<\/p>\n<p data-start=\"4974\" data-end=\"4986\"><strong data-start=\"4974\" data-end=\"4986\">Studies:<\/strong><\/p>\n<p data-start=\"4988\" data-end=\"5552\">A stimulating effect of Ademetionine (S-Adenosylmethionine) on chondrocytes was demonstrated in studies using human chondrocyte cultures (Harmand, Vilamitjana, Maloche et al., 1987), and it was also shown to increase sulfate incorporation into proteoglycans (Harnand, Vilamitjana, Maoche et al., 1987). Furthermore, Ademetionine (S-Adenosylmethionine) enters synovial fluid after oral doses of 400 mg (Giulidori, Cortellaro, Moreo et al., 1984), suggesting a plausible mechanism by which Ademetionine (S-Adenosylmethionine) can affect and alleviate osteoarthritis.<\/p>\n<p data-start=\"5554\" data-end=\"5566\"><strong data-start=\"5554\" data-end=\"5566\">Sources:<\/strong><\/p>\n<p data-start=\"5568\" data-end=\"5759\">Hosea Blewett, HJ. (2008). Exploring the mechanisms behind S-adenosylmethionine (SAMe) in the treatment of osteoarthritis. Crit Rev Food Sci Nutr. 48(5): 458\u2010463 doi:10.1080\/10408390701429526<\/p>\n<p data-start=\"5761\" data-end=\"6004\">Hardy M., Coulter I., Morton SC, et al. (2002). S-adenosyl-L-methionine for the treatment of depression, arthrosis, and liver diseases. Evidence Reports \/ Technology Assessments, No. 64. Rockville (MD): Health Research and Quality Agency (USA)<\/p>\n<p data-start=\"6006\" data-end=\"6100\"><strong data-start=\"6006\" data-end=\"6100\">ECP\u00ae &#8211; Epigenetic Cartilage Protector contains naturally occurring substances in the body:<\/strong><\/p>\n<p data-start=\"6102\" data-end=\"6562\"><strong data-start=\"6102\" data-end=\"6141\">Ademetionine (S-Adenosylmethionine)<\/strong><br data-start=\"6141\" data-end=\"6144\" \/>The production of S-Adenosylmethionine (Ademetionine) in humans primarily occurs in the liver. A liver-healthy adult under 30 synthesizes approximately 8 grams of S-Adenosylmethionine per day. The natural occurrence and biosynthesis of Ademetionine in liver cells decline after the age of 35. This age-related decrease in Ademetionine leads to DNA hypomethylation (under-methylation), contributing to various diseases.<\/p>\n<p data-start=\"6564\" data-end=\"6786\">To your benefit, we use <strong data-start=\"6588\" data-end=\"6600\">ADOGRAN\u00ae<\/strong>, a coated (acid- and water-resistant) granulate of Ademetionine, with an acid-resistant capsule shell protecting the integrity of the active form of S-Adenosylmethionine (Ademetionine).<\/p>\n<p data-start=\"6788\" data-end=\"7019\"><strong data-start=\"6788\" data-end=\"6803\">Vitamin B12<\/strong><br data-start=\"6803\" data-end=\"6806\" \/>Supports the metabolic functions of our brain cells, maintaining normal nervous system function and psychological functions (as per Regulation (EU) No. 432\/2012). Vitamin B12 also supports Ademetionine production.<\/p>\n<p data-start=\"7021\" data-end=\"7307\">We use <strong data-start=\"7028\" data-end=\"7048\">HYDROXOCOBALAMIN<\/strong>, a form of Vitamin B12 with the best depot effect in brain cells, as it binds well to the body&#8217;s transport molecules, circulating in the blood for an extended period and easily converting into one of the bioactive forms, Methylcobalamin or Adenosylcobalamin.<\/p>\n<p data-start=\"7309\" data-end=\"7624\" data-is-last-node=\"\"><strong data-start=\"7309\" data-end=\"7323\">Folic Acid<\/strong><br data-start=\"7323\" data-end=\"7326\" \/>Contributes to normal amino acid synthesis and supports the availability of the essential amino acid Methionine in the one-carbon cycle. Folic acid also contributes to normal homocysteine metabolism, helping avoid the risk factor of hyperhomocysteinemia, and supports normal psychological function.<\/p>\n<p>We can, across the restrictions set by our genes, control how healthy we are. Epigenetics enables us to.<\/p>\n<p>Sections of our genetic information can be switched on or off, for example by using transmethylation. Using this mechanism, segments of our genes may be silenced and others activated. Gene activity can be modulated without actually changing the gene sequence.<\/p>\n<p>Fact: <strong>Ademetionine<\/strong> is the most important biological methyl group donor in our cells employed for this important epigenetic process. <strong>ECP\u00ae \u2013 Epigenetic Cartilage Protector<\/strong>\u00ae contains ademetionine.<\/p>\n<p>.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-8vc5if-93f25071e2237f185de4f6450624b59a\">\n.flex_column.av-8vc5if-93f25071e2237f185de4f6450624b59a{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-8vc5if-93f25071e2237f185de4f6450624b59a av_two_fifth  avia-builder-el-6  el_after_av_three_fifth  el_before_av_hr  flex_column_div av-animated-generic right-to-left av-zero-column-padding  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-8n71tb-5260b2d583a45a81e691bfc3925ee3f4\">\n.avia-image-container.av-8n71tb-5260b2d583a45a81e691bfc3925ee3f4 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-8n71tb-5260b2d583a45a81e691bfc3925ee3f4 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-8n71tb-5260b2d583a45a81e691bfc3925ee3f4 av-styling- avia_animated_image av-animated-when-visible-95 right-to-left avia-align-center  avia-builder-el-7  el_before_av_textblock  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-1280 avia-img-lazy-loading-not-1280 avia_image ' src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-scaled.jpg\" alt='Epigenetics Athrosis Cartilage' title='Epigenetics Arthrosis Cartilage'  height=\"1773\" width=\"2560\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-scaled.jpg 2560w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-450x312.jpg 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-300x208.jpg 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-768x532.jpg 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-1030x714.jpg 1030w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-1500x1039.jpg 1500w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/Knie-Laufen-WP-705x488.jpg 705w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-8jualb-66bfbffe876754143d8749ef1fa8f104 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"text-align: center;\"><strong>ECP\u00ae &#8211; Epigenetic Cartilage Protector<\/strong><br \/>\n<strong>30 capsules protect for 30 days<\/strong><\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-8eymin-a60f1e0fd99117726841a87802999819\">\n#top .hr.hr-invisible.av-8eymin-a60f1e0fd99117726841a87802999819{\nheight:15px;\n}\n<\/style>\n<div  class='hr av-8eymin-a60f1e0fd99117726841a87802999819 hr-invisible  avia-builder-el-9  el_after_av_two_fifth  el_before_av_two_fifth '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-87g9hr-453aac9e49e75f907a9e7f3dea7bbbd0\">\n.flex_column.av-87g9hr-453aac9e49e75f907a9e7f3dea7bbbd0{\nborder-radius:0px 0px 0px 0px;\npadding:3% 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-87g9hr-453aac9e49e75f907a9e7f3dea7bbbd0 av_two_fifth  avia-builder-el-10  el_after_av_hr  el_before_av_three_fifth  first flex_column_div av-animated-generic left-to-right  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-82i687-8facd9792f654193b17039e9620fe633\">\n.avia-image-container.av-82i687-8facd9792f654193b17039e9620fe633 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-82i687-8facd9792f654193b17039e9620fe633 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-82i687-8facd9792f654193b17039e9620fe633 av-styling-no-styling av-hover-grow av-img-linked avia_animated_image av-animated-when-visible-95 fade-in avia-align-center  avia-builder-el-11  el_before_av_textblock  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><a href=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-1030x579.png\" data-srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-1030x579.png 1030w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-450x253.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-300x169.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-768x432.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-1500x844.png 1500w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-705x397.png 705w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e.png 1920w\" data-sizes=\"(max-width: 1030px) 100vw, 1030px\" class='avia_image '  aria-label='DNA Transmethylation NUGENIS products support the DNA Methylation with substitution with ademetionine'><img decoding=\"async\" class='wp-image-2882 avia-img-lazy-loading-not-2882 avia_image ' src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e.png\" alt='DNA Transmethylation NUGENIS products support the DNA Methylation with substitution with ademetionine' title='DNA Transmethylation NUGENIS products support the DNA Methylation with substitution with ademetionine'  height=\"1080\" width=\"1920\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e.png 1920w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-450x253.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-300x169.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-768x432.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-1030x579.png 1030w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-1500x844.png 1500w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/transmetylation-e-705x397.png 705w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/><\/a><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-7vg6pj-2ddb5c92bd1874312e4acceecbf2a8a2\">\n#top .av_textblock_section.av-7vg6pj-2ddb5c92bd1874312e4acceecbf2a8a2 .avia_textblock{\nfont-size:13px;\n}\n<\/style>\n<section  class='av_textblock_section av-7vg6pj-2ddb5c92bd1874312e4acceecbf2a8a2 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"text-align: center;\"><strong>Transmethylation<\/strong><\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-7ncl0v-6e4755c4e4f1513c3dd5a8921c10d123\">\n.flex_column.av-7ncl0v-6e4755c4e4f1513c3dd5a8921c10d123{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-7ncl0v-6e4755c4e4f1513c3dd5a8921c10d123 av_three_fifth  avia-builder-el-13  el_after_av_two_fifth  el_before_av_hr  flex_column_div av-animated-generic right-to-left av-zero-column-padding  '     ><section  class='av_textblock_section av-7k1b1j-3ed9b67e5603131a0aea35226d713554 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>Ademetionine<\/strong> is a methyl group donor, resulting in methylation and silencing of the genetic information in the DNA of the epigenome of MaoB.\u00a0Ademetionine is linked to four key processes in our metabolism.<\/p>\n<p>Transmethylation is a good example: methyl groups (-CH3) are attached to genes via transmethylation. Genes can be switched on or off by transmethylation and this in turn has an impact on the production of enzymes and proteins.<\/p>\n<p>An important epigenetic control mechanism is transcriptional silencing through methylation: CpG islands in the gene promoter of monoamine oxidase B (MaoB) can be silenced via methylation. This process is dependent on the availability of the methyl group donor ademetionine.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-7bag5z-da6a84ae89a1d27f1871ba5d214d3c26\">\n#top .hr.hr-invisible.av-7bag5z-da6a84ae89a1d27f1871ba5d214d3c26{\nheight:15px;\n}\n<\/style>\n<div  class='hr av-7bag5z-da6a84ae89a1d27f1871ba5d214d3c26 hr-invisible  avia-builder-el-15  el_after_av_three_fifth  el_before_av_three_fifth '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-pue87-ae636d370a8e66308dda5c65e043d6f9\">\n.flex_column.av-pue87-ae636d370a8e66308dda5c65e043d6f9{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-pue87-ae636d370a8e66308dda5c65e043d6f9 av_three_fifth  avia-builder-el-16  el_after_av_hr  el_before_av_two_fifth  first flex_column_div av-animated-generic left-to-right av-zero-column-padding  '     ><section  class='av_textblock_section av-6z364f-8d6de722ac6f1a66edabb82daa4e8e32 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>Epigenetics secures and protects our health<\/strong><\/p>\n<p>Each and every one of the 200 different cell types in our body contains an identical genome. Then how is it possible, that all these different cell types carry out such vastly different functions? The answer can be found in the make-up of their epigenome. The epigenome acts as a set of genetic switches. It regulates how a cell and as a result how our body operates in determining which genes in our genome need to be switched on or off.<\/p>\n<p>Ademetionine consists of the essential amino acid L-methionine and adenosine triphosphate (ATP), a universal source of energy in our cells. While we cannot change our DNA (our inherited genes), we can very much influence the manner in which the genetic information is used via epigenetic modulation. A <strong>healthy lifestyle, positive attitude<\/strong> and a <strong>good diet<\/strong> can trigger <strong>healthy gene expression<\/strong> via epigenetic processes. Cell protective genes are switched on and cell destructive genes will be switched off.<\/p>\n<p>The dispositional supply of methionine is enabled by the vitamin B12 dependent methylation of homocysteine (HCY) to methionine. Ultimately, ademetionine is generated from the essential amino acid methionine and adenosine triphosphate (ATP), the universal source of energy in cells.<\/p>\n<p><strong>But there is one obstacle our body has to overcome:<\/strong><\/p>\n<p>A deficiency in ademetionine and vitamin B12 in our metabolism is the rule in people aged 40 and above. Our body simply does not make sufficient amounts of ademetionine anymore resulting in <strong>ademetionine deficiency.<\/strong> In addition, the mucosal lining of our stomach atrophies with age. This in turn reduces the uptake of vitamin B12, causing <strong>vitamin B12 deficiency<\/strong>.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-6xssdb-885c33b981efece7268f824c4594ac06\">\n.flex_column.av-6xssdb-885c33b981efece7268f824c4594ac06{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-6xssdb-885c33b981efece7268f824c4594ac06 av_two_fifth  avia-builder-el-18  el_after_av_three_fifth  el_before_av_hr  flex_column_div av-animated-generic right-to-left av-zero-column-padding  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-6rjqin-b0061c43b9572415150b1e7ee45ad884\">\n.avia-image-container.av-6rjqin-b0061c43b9572415150b1e7ee45ad884 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-6rjqin-b0061c43b9572415150b1e7ee45ad884 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-6rjqin-b0061c43b9572415150b1e7ee45ad884 av-styling-no-styling av-img-linked avia_animated_image av-animated-when-visible-95 fade-in avia-align-center  avia-builder-el-19  el_before_av_textblock  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><a href=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-1030x580.png\" data-srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-1030x580.png 1030w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-450x253.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-300x169.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-768x432.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-1500x844.png 1500w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-705x397.png 705w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e.png 1921w\" data-sizes=\"(max-width: 1030px) 100vw, 1030px\" class='avia_image '  aria-label='NUGENIS products support the carbon cycle with the substitution of ademetionine'><img decoding=\"async\" class='wp-image-2822 avia-img-lazy-loading-not-2822 avia_image ' src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e.png\" alt='' title='NUGENIS products support the carbon cycle with the substitution of ademetionine'  height=\"1081\" width=\"1921\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e.png 1921w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-450x253.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-300x169.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-768x432.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-1030x580.png 1030w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-1500x844.png 1500w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/11\/one-carbon-nugenis-e-705x397.png 705w\" sizes=\"(max-width: 1921px) 100vw, 1921px\" \/><\/a><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-6lf22n-4a31987edb74064e554e1afabcf09104\">\n#top .av_textblock_section.av-6lf22n-4a31987edb74064e554e1afabcf09104 .avia_textblock{\nfont-size:12px;\n}\n<\/style>\n<section  class='av_textblock_section av-6lf22n-4a31987edb74064e554e1afabcf09104 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>One Carbon Cycle<\/strong><\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-6ccnav-fae61f5465fef9839f1b4cd4da693641\">\n#top .hr.hr-invisible.av-6ccnav-fae61f5465fef9839f1b4cd4da693641{\nheight:15px;\n}\n<\/style>\n<div  class='hr av-6ccnav-fae61f5465fef9839f1b4cd4da693641 hr-invisible  avia-builder-el-21  el_after_av_two_fifth  el_before_av_two_fifth '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-659dhj-2d54bca180a55613c455aee44e4bf96e\">\n.flex_column.av-659dhj-2d54bca180a55613c455aee44e4bf96e{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-659dhj-2d54bca180a55613c455aee44e4bf96e av_two_fifth  avia-builder-el-22  el_after_av_hr  el_before_av_three_fifth  first flex_column_div av-animated-generic left-to-right av-zero-column-padding  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-61qc6n-f9c3a17bf9df70d25cbd85dc9db5784e\">\n.avia-image-container.av-61qc6n-f9c3a17bf9df70d25cbd85dc9db5784e img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-61qc6n-f9c3a17bf9df70d25cbd85dc9db5784e .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-61qc6n-f9c3a17bf9df70d25cbd85dc9db5784e av-styling-no-styling av-img-linked avia_animated_image av-animated-when-visible-95 fade-in avia-align-center  avia-builder-el-23  el_before_av_textblock  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><a href=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik.png\" data-srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik.png 968w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-450x341.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-300x227.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-768x582.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-705x534.png 705w\" data-sizes=\"(max-width: 968px) 100vw, 968px\" class='avia_image '  aria-label='grafik'><img decoding=\"async\" class='wp-image-191 avia-img-lazy-loading-not-191 avia_image ' src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik.png\" alt='' title='grafik'  height=\"733\" width=\"968\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik.png 968w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-450x341.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-300x227.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-768x582.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/grafik-705x534.png 705w\" sizes=\"(max-width: 968px) 100vw, 968px\" \/><\/a><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5upqtj-e92171b1722d6805e495c86ec57f2547\">\n#top .av_textblock_section.av-5upqtj-e92171b1722d6805e495c86ec57f2547 .avia_textblock{\nfont-size:13px;\n}\n<\/style>\n<section  class='av_textblock_section av-5upqtj-e92171b1722d6805e495c86ec57f2547 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"text-align: center;\"><strong>DNA methylation is related to our age<\/strong><\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5o9yon-77e58fd87af28929a63d3f5e27b82803\">\n.flex_column.av-5o9yon-77e58fd87af28929a63d3f5e27b82803{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-5o9yon-77e58fd87af28929a63d3f5e27b82803 av_three_fifth  avia-builder-el-25  el_after_av_two_fifth  el_before_av_hr  flex_column_div av-animated-generic right-to-left av-zero-column-padding  '     ><section  class='av_textblock_section av-5lffbr-fb7bfe1a6bc58dfd2c43906d4f46b531 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Because of this mechanism, DNA methylation is linked to our age.<\/p>\n<p>If transcriptional silencing through methylation of CpG islands in the promoter of the monoamine oxidase B (MaoB) gene is less efficient, more dopamine will be degraded leading to <strong>dopamine depletion<\/strong> during transfer of information between brain cells.<\/p>\n<p>It is critical to maintain the supply of <strong>dopamine<\/strong> to the brain in a physiological manner as dopamine is the brain transmitter supporting cognitive performance and also because it is linked to emotions, mobility, happiness and the reward system and also directly and indirectly affects the immune system.<\/p>\n<p>The brain transmitter <strong>serotonin<\/strong> has mood-lifting effects and simultaneously, as it is also a GABA mimetic, reduces pain and acts as a muscle relaxant. Serotonin degradation also increases and will lead to <strong>serotonin deprivation<\/strong>. Muscle tensions will perceived to be more severe.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5e0yqf-cb201e78153e3fd6aa5ce743025aaec1\">\n#top .hr.hr-invisible.av-5e0yqf-cb201e78153e3fd6aa5ce743025aaec1{\nheight:15px;\n}\n<\/style>\n<div  class='hr av-5e0yqf-cb201e78153e3fd6aa5ce743025aaec1 hr-invisible  avia-builder-el-27  el_after_av_three_fifth  avia-builder-el-last '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='av_section_3'  class='avia-section av-55po1j-fec5914bd89ece425b183168dfa388fe main_color avia-section-default avia-no-border-styling  avia-builder-el-28  el_after_av_section  el_before_av_section  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-519'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-53ltbz-794291991f41a31a7fa8397da6b44813\">\n.flex_column.av-53ltbz-794291991f41a31a7fa8397da6b44813{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-53ltbz-794291991f41a31a7fa8397da6b44813 av_one_full  avia-builder-el-29  avia-builder-el-no-sibling  first flex_column_div av-animated-generic left-to-right av-zero-column-padding  '     ><section  class='av_textblock_section av-4tfgaf-45cfca25dde7160b3e18dd65399817a2 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"text-align: justify;\">To achieve an <strong>elementary level of protection, <\/strong>consistant supplementation of ademetionine and vitamin B12 is necessary and regularly taking <strong>ECP<\/strong><strong>\u00ae &#8211; Epigenetic Cartilage Protector<\/strong> will counteract a deficiency of ademetionine and vitamin B12.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-4qw25z-2f4a0bf9cc2dd1eefa9bc2b17ac5cad4\">\n#top .hr.hr-invisible.av-4qw25z-2f4a0bf9cc2dd1eefa9bc2b17ac5cad4{\nheight:15px;\n}\n<\/style>\n<div  class='hr av-4qw25z-2f4a0bf9cc2dd1eefa9bc2b17ac5cad4 hr-invisible  avia-builder-el-31  el_after_av_textblock  el_before_av_textblock '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<section  class='av_textblock_section av-4hpqyn-888d99ed95a286009d7ec58049f62fae '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h3 style=\"text-align: justify;\">Cartilage protection<\/h3>\n<p>Experimental studies show that <strong>ademetionine<\/strong> increases chondrocyte-proteoglycan synthesis and its rate of proliferation. <strong>Ademetionine<\/strong> induces the synthesis of polyamines which in turn stabilise the polyanionic macromolecules of proteoglycans and protect them from being targeted by proteolytic and glycolytic enzymes.<strong>\u00a0Ademetionine<\/strong> supports healthy basal conditions in the synovial cells in our joints.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-4beg3b-3343c0a23ceb0f5c1693f9f9b266ddf0\">\n#top .hr.hr-invisible.av-4beg3b-3343c0a23ceb0f5c1693f9f9b266ddf0{\nheight:15px;\n}\n<\/style>\n<div  class='hr av-4beg3b-3343c0a23ceb0f5c1693f9f9b266ddf0 hr-invisible  avia-builder-el-33  el_after_av_textblock  el_before_av_textblock '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<section  class='av_textblock_section av-49z6ev-71c79bfcf85679eb6d314d4748577a6d '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h3>Systemic Long-Term Therapy Using Glucocorticoid Hormones<\/h3>\n<p>Dexamethasone is a strong synthetic glucocorticoid hormone that increases MaoB activity. This results in <strong>hypercortisolaemia<\/strong>. Regularly taking <strong>ECP\u00ae\u00a0<\/strong><strong>&#8211; Epigenetic Cartilage Protector<\/strong> silences MaoB expression at genetic level and also protects brain cells from cortisol induced alteration (cell death).<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-440r9z-fd383b74cf451e38dc455074981624de\">\n#top .hr.hr-invisible.av-440r9z-fd383b74cf451e38dc455074981624de{\nheight:15px;\n}\n<\/style>\n<div  class='hr av-440r9z-fd383b74cf451e38dc455074981624de hr-invisible  avia-builder-el-35  el_after_av_textblock  el_before_av_textblock '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<section  class='av_textblock_section av-3yb0n3-0231ea4c59dc1f20e6738afeeb2a7d0e '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h3>Cortisol activates MaoB gene expression<\/h3>\n<p>Monoamine oxidase B (MaoB) is the enzyme responsible for the degradation of brain messenger molecules dopamine, noradrenaline, noradrenaline and serotonin.<\/p>\n<p>An important modulating mechanism employed in epigenetics is <strong>stopping the transcription<\/strong> of the promoter gene of monoamine oxidase B (MaoB). This phenomenon is referred to as <strong>\u201cgene silencing\u201d<\/strong> \u2013 targeted inactivation of the gene location of MaoB: active gene expression is only possible if the gene is not methylated.<\/p>\n<p><strong>Ademetionine<\/strong> is a methyl group donor, resulting in methylation and silencing of the genetic information in the DNA of the epigenome of MaoB.<\/p>\n<\/div><\/section><\/p><\/div>\n<\/p>\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-3rz6hb-0f25ca902a99ddb454fc654acbf3b72e\">\n.avia-section.av-3rz6hb-0f25ca902a99ddb454fc654acbf3b72e{\nbackground-color:#fafafa;\nbackground-image:unset;\n}\n<\/style>\n<div id='av_section_4'  class='avia-section av-3rz6hb-0f25ca902a99ddb454fc654acbf3b72e main_color avia-section-default avia-no-border-styling  avia-builder-el-37  el_after_av_section  el_before_av_section  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-519'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-3iucin-558e77710e5b3343fb94ee8bf28be5af\">\n.flex_column.av-3iucin-558e77710e5b3343fb94ee8bf28be5af{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-3iucin-558e77710e5b3343fb94ee8bf28be5af av_three_fifth  avia-builder-el-38  el_before_av_two_fifth  avia-builder-el-first  first flex_column_div av-animated-generic left-to-right av-zero-column-padding  '     ><section  class='av_textblock_section av-3fyqkv-9f70679c6a142ad7a60b4f4c68d69b9a '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h2>ECP\u00ae \u2013 EPIGENETIC CARTILAGE PROTECTOR<\/h2>\n<p>Contains these five naturally in our body occurring substances:<\/p>\n<p><strong>Ademetionine<\/strong> is a metabolic product that can be found in all cells in our body. After water and ATP, the universally available and immediately usable source of energy, it is the third most abundant molecule in our body. Its physiological level in the cell decreases continuously from age 40 onwards.<\/p>\n<p><strong>Vitamin B12<\/strong> supports those metabolic processes in our brain cells important for maintaining a healthy nervous system and normal mental performance. Vitamin B12 is involved in ademetionine production.<\/p>\n<p><strong>Vitamin B6<\/strong> contributes to healthy energy metabolism, promotes healthy protein metabolism and supports a healthy immune system.<\/p>\n<p><strong>Folic acid<\/strong> assists with healthy amino acid synthesis and supports the dispositional supply of the essential amino acid methionine in the one-carbon metabolic cycle.<\/p>\n<p><strong>Folic acid<\/strong> is involved in normal homocysteine metabolism.<\/p>\n<p><strong>Folic acid <\/strong>is essential for good mental health as ATP-activated methionine is produced from dispositionally supplied methionine and is involved in epigenetic control mechanisms to maintain normal mental functions.<\/p>\n<p><strong>Folic acid<\/strong> contributes to a healthy immune system.<\/p>\n<p><strong>Zinc<\/strong> helps to protect cells from oxidative stress. Oxidative stress is the main cause of cell aging.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-37e2p3-6ed4631b02a93011424dd2680755112c\">\n.flex_column.av-37e2p3-6ed4631b02a93011424dd2680755112c{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-37e2p3-6ed4631b02a93011424dd2680755112c av_two_fifth  avia-builder-el-40  el_after_av_three_fifth  avia-builder-el-last  flex_column_div av-animated-generic right-to-left av-zero-column-padding  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-32d39j-a6a712a50e35c5f8b0e2aa3bbac6c8ad\">\n.avia-image-container.av-32d39j-a6a712a50e35c5f8b0e2aa3bbac6c8ad img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-32d39j-a6a712a50e35c5f8b0e2aa3bbac6c8ad .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-32d39j-a6a712a50e35c5f8b0e2aa3bbac6c8ad av-styling-no-styling avia_animated_image av-animated-when-visible-95 fade-in avia-align-center  avia-builder-el-41  el_before_av_hr  avia-builder-el-first '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-233 avia-img-lazy-loading-not-233 avia_image ' src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-180x180.png\" alt='' title='EAP'  height=\"180\" width=\"180\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-180x180.png 180w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-450x450.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-100x100.png 100w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-80x80.png 80w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-300x300.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-768x768.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-36x36.png 36w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP-705x705.png 705w, https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/EAP.png 1000w\" sizes=\"(max-width: 180px) 100vw, 180px\" \/><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2yxf3r-59204f5d648b9200d8b284f49bca32ad\">\n#top .hr.hr-invisible.av-2yxf3r-59204f5d648b9200d8b284f49bca32ad{\nheight:50px;\n}\n<\/style>\n<div  class='hr av-2yxf3r-59204f5d648b9200d8b284f49bca32ad hr-invisible  avia-builder-el-42  el_after_av_image  avia-builder-el-last '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p><\/div>\n\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2sxl1j-119c32f33bc0a46bbff8533a949c61c2\">\n.avia-section.av-2sxl1j-119c32f33bc0a46bbff8533a949c61c2 .av-parallax .av-parallax-inner{\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/nugenis_home_10.jpg);\nbackground-position:50% 100%;\nbackground-attachment:scroll;\n}\n<\/style>\n<div id='av_section_5'  class='avia-section av-2sxl1j-119c32f33bc0a46bbff8533a949c61c2 main_color avia-section-default avia-no-shadow  avia-builder-el-43  el_after_av_section  el_before_av_section  avia-full-stretch av-parallax-section avia-bg-style-parallax av-minimum-height av-minimum-height-25 av-height-25  container_wrap sidebar_right'  data-section-bg-repeat='stretch' data-av_minimum_height_pc='25' data-av_min_height_opt='25'><div class='av-parallax' data-avia-parallax-ratio='0.3' ><div class='av-parallax-inner main_color avia-full-stretch'><\/div><\/div><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-519'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2msipj-95deefc44c685be5fad9d1d67fdf3b73\">\n.flex_column.av-2msipj-95deefc44c685be5fad9d1d67fdf3b73{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-2msipj-95deefc44c685be5fad9d1d67fdf3b73 av_one_fourth  avia-builder-el-44  el_before_av_one_fourth  avia-builder-el-first  first flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2fr9fb-c4daf053e5974af072ca5044f5eedc1c\">\n.iconbox.av-2fr9fb-c4daf053e5974af072ca5044f5eedc1c .iconbox_icon{\nbackground-color:#0081b9;\nborder:1px solid #0081b9;\ncolor:#ffffff;\n}\n.iconbox.av-2fr9fb-c4daf053e5974af072ca5044f5eedc1c .iconbox_icon.avia-svg-icon svg:first-child{\nfill:#ffffff;\nstroke:#ffffff;\n}\n<\/style>\n<article  class='iconbox iconbox_top av-2fr9fb-c4daf053e5974af072ca5044f5eedc1c  avia-builder-el-45  avia-builder-el-no-sibling  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: GLUTEN FREE\"><div class='iconbox_icon heading-color avia-iconfont avia-font-entypo-fontello' data-av_icon='\ue8b8' data-av_iconfont='entypo-fontello'  ><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >GLUTEN FREE<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-28gyiv-f019347c196271b013d667f3c9133119\">\n.flex_column.av-28gyiv-f019347c196271b013d667f3c9133119{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-28gyiv-f019347c196271b013d667f3c9133119 av_one_fourth  avia-builder-el-46  el_after_av_one_fourth  el_before_av_one_fourth  flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-23fwrz-2c7cc620ee46fb67348dc663ec0ccb0a\">\n.iconbox.av-23fwrz-2c7cc620ee46fb67348dc663ec0ccb0a .iconbox_icon{\nbackground-color:#0081b9;\nborder:1px solid #0081b9;\ncolor:#ffffff;\n}\n.iconbox.av-23fwrz-2c7cc620ee46fb67348dc663ec0ccb0a .iconbox_icon.avia-svg-icon svg:first-child{\nfill:#ffffff;\nstroke:#ffffff;\n}\n<\/style>\n<article  class='iconbox iconbox_top av-23fwrz-2c7cc620ee46fb67348dc663ec0ccb0a  avia-builder-el-47  avia-builder-el-no-sibling  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: LACTOSE FREE\"><div class='iconbox_icon heading-color avia-iconfont avia-font-entypo-fontello' data-av_icon='\ue8b8' data-av_iconfont='entypo-fontello'  ><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >LACTOSE FREE<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1w9tvr-eb2a6b9b5a9c75608877bc2b6f9c2f48\">\n.flex_column.av-1w9tvr-eb2a6b9b5a9c75608877bc2b6f9c2f48{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-1w9tvr-eb2a6b9b5a9c75608877bc2b6f9c2f48 av_one_fourth  avia-builder-el-48  el_after_av_one_fourth  el_before_av_one_fourth  flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1rs9iv-7672a4158f11ab9cb3453ab76c06ab25\">\n.iconbox.av-1rs9iv-7672a4158f11ab9cb3453ab76c06ab25 .iconbox_icon{\nbackground-color:#0081b9;\nborder:1px solid #0081b9;\ncolor:#ffffff;\n}\n.iconbox.av-1rs9iv-7672a4158f11ab9cb3453ab76c06ab25 .iconbox_icon.avia-svg-icon svg:first-child{\nfill:#ffffff;\nstroke:#ffffff;\n}\n<\/style>\n<article  class='iconbox iconbox_top av-1rs9iv-7672a4158f11ab9cb3453ab76c06ab25  avia-builder-el-49  avia-builder-el-no-sibling  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: FRUCTOSE FREE\"><div class='iconbox_icon heading-color avia-iconfont avia-font-entypo-fontello' data-av_icon='\ue8b8' data-av_iconfont='entypo-fontello'  ><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >FRUCTOSE FREE<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5uibz-c26a0d3735cdb3ed5ff598c83b4b2349\">\n.flex_column.av-5uibz-c26a0d3735cdb3ed5ff598c83b4b2349{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-5uibz-c26a0d3735cdb3ed5ff598c83b4b2349 av_one_fourth  avia-builder-el-50  el_after_av_one_fourth  avia-builder-el-last  flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-52y1r-1f16aee178af6c57a38d033d15a23fe2\">\n.iconbox.av-52y1r-1f16aee178af6c57a38d033d15a23fe2 .iconbox_icon{\nbackground-color:#0081b9;\nborder:1px solid #0081b9;\ncolor:#ffffff;\n}\n.iconbox.av-52y1r-1f16aee178af6c57a38d033d15a23fe2 .iconbox_icon.avia-svg-icon svg:first-child{\nfill:#ffffff;\nstroke:#ffffff;\n}\n<\/style>\n<article  class='iconbox iconbox_top av-52y1r-1f16aee178af6c57a38d033d15a23fe2  avia-builder-el-51  avia-builder-el-no-sibling  main_color'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconbox_content\"><header class=\"entry-content-header\" aria-label=\"Icon: VEGAN\"><div class='iconbox_icon heading-color avia-iconfont avia-font-entypo-fontello' data-av_icon='\ue8b8' data-av_iconfont='entypo-fontello'  ><\/div><h3 class='iconbox_content_title '  itemprop=\"headline\" >VEGAN<\/h3><\/header><div class='iconbox_content_container '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><\/div>\n\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-16m2hb-a532bf362d3f372602381e9c129f85c1\">\n.avia-section.av-16m2hb-a532bf362d3f372602381e9c129f85c1 .av-parallax .av-parallax-inner{\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/NuegnisHome_bg-1.png);\nbackground-position:0% 0%;\nbackground-attachment:scroll;\n}\n<\/style>\n<div id='shop'  class='avia-section av-16m2hb-a532bf362d3f372602381e9c129f85c1 main_color avia-section-default avia-no-shadow  avia-builder-el-52  el_after_av_section  avia-builder-el-last  av-parallax-section avia-bg-style-parallax container_wrap sidebar_right'  data-section-bg-repeat='no-repeat'><div class='av-parallax' data-avia-parallax-ratio='0.3' ><div class='av-parallax-inner main_color avia-full-stretch'><\/div><\/div><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-519'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1531rr-e466d944abb1a49b4339228f0b470237\">\n#top .av-special-heading.av-1531rr-e466d944abb1a49b4339228f0b470237{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-1531rr-e466d944abb1a49b4339228f0b470237 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-1531rr-e466d944abb1a49b4339228f0b470237 .av-subheading{\nfont-size:20px;\n}\n<\/style>\n<div  class='av-special-heading av-1531rr-e466d944abb1a49b4339228f0b470237 av-special-heading-h1 blockquote modern-quote modern-centered  avia-builder-el-53  el_before_av_hr  avia-builder-el-first '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >NUGENIS PRODUCTS &#8211; ORDER<\/h1><div class='av-subheading av-subheading_below'><p>Conveniently order from our online shop<\/p>\n<\/div><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<div  class='hr av-xvur3-394e1c8498a0964282d33bae157b3997 hr-short  avia-builder-el-54  el_after_av_heading  el_before_av_one_full  hr-center'><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mbhjz-ee35ceb3dc3d3c284436a843e75862ff\">\n.flex_column.av-mbhjz-ee35ceb3dc3d3c284436a843e75862ff{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-mbhjz-ee35ceb3dc3d3c284436a843e75862ff av_one_full  avia-builder-el-55  el_after_av_hr  avia-builder-el-last  first flex_column_div av-zero-column-padding  '     ><div  class='avia-product-slider-container av-gfvhz-c5e8ff9b7a2caa0f58685e1a7da76eb2 template-shop avia-content-slider avia-content-slider-active shop_columns_4  avia-builder-el-56  avia-builder-el-no-sibling  avia-content-slider-even  avia-builder-el-56  avia-builder-el-no-sibling  av-slideshow-ui av-control-default av-nav-arrows-visible av-slider-hover-pause av-slideshow-manual av-loop-once av-loop-manual-endless avia-product-slider1' data-slideshow-options=\"{&quot;animation&quot;:&quot;fade&quot;,&quot;autoplay&quot;:false,&quot;loop_autoplay&quot;:&quot;once&quot;,&quot;interval&quot;:5,&quot;loop_manual&quot;:&quot;manual-endless&quot;,&quot;autoplay_stopper&quot;:false,&quot;noNavigation&quot;:false,&quot;bg_slider&quot;:false,&quot;keep_padding&quot;:false,&quot;hoverpause&quot;:true,&quot;show_slide_delay&quot;:0}\"><div class='avia-content-slider-inner'><ul class=\"products slide-entry-wrap\"><li class=\"product type-product post-3344 status-publish first instock has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<div class='inner_product main_color wrapped_style noLightbox  av-product-class-'><a href=\"https:\/\/nugenis.eu\/en\/produkt\/ebp-epigenetic-brain-protector\/\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><div class=\"thumbnail_container\"><img decoding=\"async\" loading=\"lazy\" width=\"450\" height=\"450\" src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-450x450.jpg\" class=\"wp-image-4600 avia-img-lazy-loading-4600 attachment-woocommerce_thumbnail size-woocommerce_thumbnail wp-post-image\" alt=\"\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-450x450.jpg 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-100x100.jpg 100w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-300x300.jpg 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-80x80.jpg 80w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-768x768.jpg 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-36x36.jpg 36w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-180x180.jpg 180w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2-705x705.jpg 705w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebp-vo2.jpg 1000w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/><span class=\"cart-loading\"><\/span><\/div><div class='inner_product_header'><div class='avia-arrow'><\/div><div class='inner_product_header_table'><div class='inner_product_header_cell'><h2 class=\"woocommerce-loop-product__title\">EBP\u00ae<br>Epigenetic Brain Protector<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi>49,90&nbsp;<span class=\"woocommerce-Price-currencySymbol\" translate=\"no\" dir=\"auto\">&euro;<\/span><\/bdi><\/span> <small class=\"woocommerce-price-suffix\">inkl. MwSt.<\/small><\/span>\n\n\n\n<\/div><\/div><\/div><\/a>\n\n\t<p class=\"wc-gzd-additional-info wc-gzd-additional-info-loop shipping-costs-info\">zzgl. <a href=\"https:\/\/nugenis.eu\/versandarten\/\" target=\"_blank\">Versandkosten<\/a><\/p>\n\n\n\t<p class=\"wc-gzd-additional-info wc-gzd-additional-info-loop product-units-wrapper product-units\">Produkt enth\u00e4lt: 0,83 <span class=\"unit\">Kapsel<\/span><\/p>\n<div class='avia_cart_buttons '><a href=\"\/en\/wp-json\/wp\/v2\/pages\/519?add-to-cart=3344\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_3344\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"3344\" data-product_sku=\"10\" aria-label=\"Add to cart: &ldquo;EBP\u00aeEpigenetic Brain Protector&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;EBP\u00ae&lt;br&gt;Epigenetic Brain Protector&rdquo; has been added to your cart\" role=\"button\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='basket' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"32\" viewBox=\"0 0 29 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-2' aria-describedby='av-svg-desc-2' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-2'>Add to cart<\/title>\n<desc id='av-svg-desc-2'>Add to cart<\/desc>\n<path d=\"M4.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM20.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM10.496 19.648q-1.152 0.32-1.088 0.736t1.408 0.416h17.984v2.432q0 0.64-0.64 0.64h-20.928q-0.64 0-0.64-0.64v-2.432l-0.32-1.472-3.136-14.528h-3.136v-2.56q0-0.64 0.64-0.64h4.992q0.64 0 0.64 0.64v2.752h22.528v8.768q0 0.704-0.576 0.832z\"><\/path>\n<\/svg><\/span>  Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_3344\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<a class=\"button show_details_button\" href=\"https:\/\/nugenis.eu\/en\/produkt\/ebp-epigenetic-brain-protector\/\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='doc-text' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"22\" height=\"32\" viewBox=\"0 0 22 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-3' aria-describedby='av-svg-desc-3' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-3'>Show Details<\/title>\n<desc id='av-svg-desc-3'>Show Details<\/desc>\n<path d=\"M6.784 17.344v-2.88h8.96v2.88h-8.96zM19.2 1.6q1.344 0 2.272 0.928t0.928 2.272v22.4q0 1.28-0.928 2.24t-2.272 0.96h-16q-1.28 0-2.24-0.96t-0.96-2.24v-22.4q0-1.344 0.96-2.272t2.24-0.928h16zM19.2 27.2v-22.4h-16v22.4h16zM15.68 8.256v2.816h-8.96v-2.816h8.96zM15.68 20.8v2.816h-8.96v-2.816h8.96z\"><\/path>\n<\/svg><\/span>  Show Details<\/a> <span class=\"button-mini-delimiter\"><\/span><\/div><\/div><\/li>\n<li class=\"product type-product post-3356 status-publish instock has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<div class='inner_product main_color wrapped_style noLightbox  av-product-class-'><a href=\"https:\/\/nugenis.eu\/en\/produkt\/ebop-epigenetic-burnout-protector\/\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><div class=\"thumbnail_container\"><img decoding=\"async\" loading=\"lazy\" width=\"450\" height=\"450\" src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-450x450.jpg\" class=\"wp-image-4597 avia-img-lazy-loading-4597 attachment-woocommerce_thumbnail size-woocommerce_thumbnail wp-post-image\" alt=\"\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-450x450.jpg 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-100x100.jpg 100w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-300x300.jpg 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-80x80.jpg 80w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-768x768.jpg 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-36x36.jpg 36w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-180x180.jpg 180w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02-705x705.jpg 705w, https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ebop-v02.jpg 1000w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/><span class=\"cart-loading\"><\/span><\/div><div class='inner_product_header'><div class='avia-arrow'><\/div><div class='inner_product_header_table'><div class='inner_product_header_cell'><h2 class=\"woocommerce-loop-product__title\">EBOP\u00ae<br>Epigenetic Burnout Protector<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi>49,90&nbsp;<span class=\"woocommerce-Price-currencySymbol\" translate=\"no\" dir=\"auto\">&euro;<\/span><\/bdi><\/span> <small class=\"woocommerce-price-suffix\">inkl. MwSt.<\/small><\/span>\n\n\n\n<\/div><\/div><\/div><\/a>\n\n\t<p class=\"wc-gzd-additional-info wc-gzd-additional-info-loop shipping-costs-info\">zzgl. <a href=\"https:\/\/nugenis.eu\/versandarten\/\" target=\"_blank\">Versandkosten<\/a><\/p>\n\n\n<div class='avia_cart_buttons '><a href=\"\/en\/wp-json\/wp\/v2\/pages\/519?add-to-cart=3356\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_3356\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"3356\" data-product_sku=\"20\" aria-label=\"Add to cart: &ldquo;EBOP\u00aeEpigenetic Burnout Protector&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;EBOP\u00ae&lt;br&gt;Epigenetic Burnout Protector&rdquo; has been added to your cart\" role=\"button\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='basket' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"32\" viewBox=\"0 0 29 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-4' aria-describedby='av-svg-desc-4' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-4'>Add to cart<\/title>\n<desc id='av-svg-desc-4'>Add to cart<\/desc>\n<path d=\"M4.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM20.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM10.496 19.648q-1.152 0.32-1.088 0.736t1.408 0.416h17.984v2.432q0 0.64-0.64 0.64h-20.928q-0.64 0-0.64-0.64v-2.432l-0.32-1.472-3.136-14.528h-3.136v-2.56q0-0.64 0.64-0.64h4.992q0.64 0 0.64 0.64v2.752h22.528v8.768q0 0.704-0.576 0.832z\"><\/path>\n<\/svg><\/span>  Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_3356\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<a class=\"button show_details_button\" href=\"https:\/\/nugenis.eu\/en\/produkt\/ebop-epigenetic-burnout-protector\/\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='doc-text' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"22\" height=\"32\" viewBox=\"0 0 22 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-5' aria-describedby='av-svg-desc-5' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-5'>Show Details<\/title>\n<desc id='av-svg-desc-5'>Show Details<\/desc>\n<path d=\"M6.784 17.344v-2.88h8.96v2.88h-8.96zM19.2 1.6q1.344 0 2.272 0.928t0.928 2.272v22.4q0 1.28-0.928 2.24t-2.272 0.96h-16q-1.28 0-2.24-0.96t-0.96-2.24v-22.4q0-1.344 0.96-2.272t2.24-0.928h16zM19.2 27.2v-22.4h-16v22.4h16zM15.68 8.256v2.816h-8.96v-2.816h8.96zM15.68 20.8v2.816h-8.96v-2.816h8.96z\"><\/path>\n<\/svg><\/span>  Show Details<\/a> <span class=\"button-mini-delimiter\"><\/span><\/div><\/div><\/li>\n<li class=\"product type-product post-7201 status-publish instock has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<div class='inner_product main_color wrapped_style noLightbox  av-product-class-'><a href=\"https:\/\/nugenis.eu\/en\/produkt\/sam-e\/\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><div class=\"thumbnail_container\"><img decoding=\"async\" loading=\"lazy\" width=\"450\" height=\"450\" src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-450x450.png\" class=\"wp-image-7715 avia-img-lazy-loading-7715 attachment-woocommerce_thumbnail size-woocommerce_thumbnail wp-post-image\" alt=\"Produktbild Sam-E\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-450x450.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-300x300.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-1030x1030.png 1030w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-80x80.png 80w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-768x768.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-1536x1536.png 1536w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-2048x2048.png 2048w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-36x36.png 36w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-180x180.png 180w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-1500x1500.png 1500w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-705x705.png 705w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-120x120.png 120w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/mockup-sam-e-transparent-4000x4000-weiss-100x100.png 100w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/><span class=\"cart-loading\"><\/span><\/div><div class='inner_product_header'><div class='avia-arrow'><\/div><div class='inner_product_header_table'><div class='inner_product_header_cell'><h2 class=\"woocommerce-loop-product__title\">SAM-e 100% active 400mg\/Capsule &#8211; 30 Capsules<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi>49,90&nbsp;<span class=\"woocommerce-Price-currencySymbol\" translate=\"no\" dir=\"auto\">&euro;<\/span><\/bdi><\/span> <small class=\"woocommerce-price-suffix\">inkl. MwSt.<\/small><\/span>\n\n\n\n<\/div><\/div><\/div><\/a>\n\n\t<p class=\"wc-gzd-additional-info wc-gzd-additional-info-loop shipping-costs-info\">zzgl. <a href=\"https:\/\/nugenis.eu\/versandarten\/\" target=\"_blank\">Versandkosten<\/a><\/p>\n\n\n<div class='avia_cart_buttons '><a href=\"\/en\/wp-json\/wp\/v2\/pages\/519?add-to-cart=7201\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_7201\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"7201\" data-product_sku=\"60\" aria-label=\"Add to cart: &ldquo;SAM-e 100% active 400mg\/Capsule - 30 Capsules&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;SAM-e 100% active 400mg\/Capsule - 30 Capsules&rdquo; has been added to your cart\" role=\"button\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='basket' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"32\" viewBox=\"0 0 29 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-6' aria-describedby='av-svg-desc-6' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-6'>Add to cart<\/title>\n<desc id='av-svg-desc-6'>Add to cart<\/desc>\n<path d=\"M4.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM20.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM10.496 19.648q-1.152 0.32-1.088 0.736t1.408 0.416h17.984v2.432q0 0.64-0.64 0.64h-20.928q-0.64 0-0.64-0.64v-2.432l-0.32-1.472-3.136-14.528h-3.136v-2.56q0-0.64 0.64-0.64h4.992q0.64 0 0.64 0.64v2.752h22.528v8.768q0 0.704-0.576 0.832z\"><\/path>\n<\/svg><\/span>  Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_7201\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<a class=\"button show_details_button\" href=\"https:\/\/nugenis.eu\/en\/produkt\/sam-e\/\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='doc-text' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"22\" height=\"32\" viewBox=\"0 0 22 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-7' aria-describedby='av-svg-desc-7' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-7'>Show Details<\/title>\n<desc id='av-svg-desc-7'>Show Details<\/desc>\n<path d=\"M6.784 17.344v-2.88h8.96v2.88h-8.96zM19.2 1.6q1.344 0 2.272 0.928t0.928 2.272v22.4q0 1.28-0.928 2.24t-2.272 0.96h-16q-1.28 0-2.24-0.96t-0.96-2.24v-22.4q0-1.344 0.96-2.272t2.24-0.928h16zM19.2 27.2v-22.4h-16v22.4h16zM15.68 8.256v2.816h-8.96v-2.816h8.96zM15.68 20.8v2.816h-8.96v-2.816h8.96z\"><\/path>\n<\/svg><\/span>  Show Details<\/a> <span class=\"button-mini-delimiter\"><\/span><\/div><\/div><\/li>\n<li class=\"product type-product post-7195 status-publish last instock has-post-thumbnail taxable shipping-taxable purchasable product-type-simple\">\n\t<div class='inner_product main_color wrapped_style noLightbox  av-product-class-'><a href=\"https:\/\/nugenis.eu\/en\/produkt\/spermidin-3mg-per-kapsel\/\" class=\"woocommerce-LoopProduct-link woocommerce-loop-product__link\"><div class=\"thumbnail_container\"><img decoding=\"async\" loading=\"lazy\" width=\"450\" height=\"450\" src=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-450x450.png\" class=\"wp-image-7372 avia-img-lazy-loading-7372 attachment-woocommerce_thumbnail size-woocommerce_thumbnail wp-post-image\" alt=\"\" srcset=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-450x450.png 450w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-300x300.png 300w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-1030x1030.png 1030w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-80x80.png 80w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-768x768.png 768w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-1536x1536.png 1536w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-2048x2048.png 2048w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-36x36.png 36w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-180x180.png 180w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-1500x1500.png 1500w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-705x705.png 705w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-120x120.png 120w, https:\/\/nugenis.eu\/wp-content\/uploads\/2024\/04\/Mockup-SPERMIDIN-weiss-100x100.png 100w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/><span class=\"cart-loading\"><\/span><\/div><div class='inner_product_header'><div class='avia-arrow'><\/div><div class='inner_product_header_table'><div class='inner_product_header_cell'><h2 class=\"woocommerce-loop-product__title\">Spermidin wheat germ extract 3mg\/Capsule &#8211; 60 Capsules<\/h2>\n\t<span class=\"price\"><span class=\"woocommerce-Price-amount amount\"><bdi>24,90&nbsp;<span class=\"woocommerce-Price-currencySymbol\" translate=\"no\" dir=\"auto\">&euro;<\/span><\/bdi><\/span> <small class=\"woocommerce-price-suffix\">inkl. MwSt.<\/small><\/span>\n\n\n\n<\/div><\/div><\/div><\/a>\n\n\t<p class=\"wc-gzd-additional-info wc-gzd-additional-info-loop shipping-costs-info\">zzgl. <a href=\"https:\/\/nugenis.eu\/versandarten\/\" target=\"_blank\">Versandkosten<\/a><\/p>\n\n\n<div class='avia_cart_buttons '><a href=\"\/en\/wp-json\/wp\/v2\/pages\/519?add-to-cart=7195\" aria-describedby=\"woocommerce_loop_add_to_cart_link_describedby_7195\" data-quantity=\"1\" class=\"button product_type_simple add_to_cart_button ajax_add_to_cart\" data-product_id=\"7195\" data-product_sku=\"62\" aria-label=\"Add to cart: &ldquo;Spermidin wheat germ extract 3mg\/Capsule - 60 Capsules&rdquo;\" rel=\"nofollow\" data-success_message=\"&ldquo;Spermidin wheat germ extract 3mg\/Capsule - 60 Capsules&rdquo; has been added to your cart\" role=\"button\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='basket' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"32\" viewBox=\"0 0 29 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-8' aria-describedby='av-svg-desc-8' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-8'>Add to cart<\/title>\n<desc id='av-svg-desc-8'>Add to cart<\/desc>\n<path d=\"M4.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM20.8 27.2q0-1.28 0.96-2.24t2.24-0.96q1.344 0 2.272 0.96t0.928 2.24q0 1.344-0.928 2.272t-2.272 0.928q-1.28 0-2.24-0.928t-0.96-2.272zM10.496 19.648q-1.152 0.32-1.088 0.736t1.408 0.416h17.984v2.432q0 0.64-0.64 0.64h-20.928q-0.64 0-0.64-0.64v-2.432l-0.32-1.472-3.136-14.528h-3.136v-2.56q0-0.64 0.64-0.64h4.992q0.64 0 0.64 0.64v2.752h22.528v8.768q0 0.704-0.576 0.832z\"><\/path>\n<\/svg><\/span>  Add to cart<\/a>\t<span id=\"woocommerce_loop_add_to_cart_link_describedby_7195\" class=\"screen-reader-text\">\n\t\t\t<\/span>\n<a class=\"button show_details_button\" href=\"https:\/\/nugenis.eu\/en\/produkt\/spermidin-3mg-per-kapsel\/\"><span class=\"avia-svg-icon avia-font-svg_entypo-fontello\" data-av_svg_icon='doc-text' data-av_iconset='svg_entypo-fontello'><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"22\" height=\"32\" viewBox=\"0 0 22 32\" preserveAspectRatio=\"xMidYMid meet\" aria-labelledby='av-svg-title-9' aria-describedby='av-svg-desc-9' role=\"graphics-symbol\" aria-hidden=\"true\">\n<title id='av-svg-title-9'>Show Details<\/title>\n<desc id='av-svg-desc-9'>Show Details<\/desc>\n<path d=\"M6.784 17.344v-2.88h8.96v2.88h-8.96zM19.2 1.6q1.344 0 2.272 0.928t0.928 2.272v22.4q0 1.28-0.928 2.24t-2.272 0.96h-16q-1.28 0-2.24-0.96t-0.96-2.24v-22.4q0-1.344 0.96-2.272t2.24-0.928h16zM19.2 27.2v-22.4h-16v22.4h16zM15.68 8.256v2.816h-8.96v-2.816h8.96zM15.68 20.8v2.816h-8.96v-2.816h8.96z\"><\/path>\n<\/svg><\/span>  Show Details<\/a> <span class=\"button-mini-delimiter\"><\/span><\/div><\/div><\/li>\n<\/ul><\/div><\/div><div class=\"clear\"><\/div><\/div>\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='after_section_6'  class='main_color av_default_container_wrap container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-519'><div class='entry-content-wrapper clearfix'>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":4594,"parent":0,"menu_order":330,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-519","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.2 (Yoast SEO v28.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Cartilage Protector - NUGENIS<\/title>\n<meta name=\"description\" content=\"ECP\u00ae - Epigenetic Cartilage Protector is a cutting-edge dietary supplement based on applied epigenetics, designed to protect and regenerate joint cartilage and discs. Featuring the biologically active form of S-Adenosyl-L-Methionine (SAM-e), this formula supports inflammation reduction, pain relief, and cellular regeneration, especially for osteoarthritis. Enriched with vitamins and trace elements, it helps maintain healthy joint and disc function.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nugenis.eu\/en\/cartilage-protector\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cartilage Protector\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nugenis.eu\/en\/cartilage-protector\/\" \/>\n<meta property=\"og:site_name\" content=\"NUGENIS\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/nugenis\/?fref=ts\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-13T14:01:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ecp-v02.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"1000\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"17 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/\",\"url\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/\",\"name\":\"Cartilage Protector - NUGENIS\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/nugenis.eu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/nugenis.eu\\\/wp-content\\\/uploads\\\/2020\\\/10\\\/ecp-v02.jpg\",\"datePublished\":\"2016-11-16T11:22:56+00:00\",\"dateModified\":\"2025-02-13T14:01:12+00:00\",\"description\":\"ECP\u00ae - Epigenetic Cartilage Protector is a cutting-edge dietary supplement based on applied epigenetics, designed to protect and regenerate joint cartilage and discs. Featuring the biologically active form of S-Adenosyl-L-Methionine (SAM-e), this formula supports inflammation reduction, pain relief, and cellular regeneration, especially for osteoarthritis. Enriched with vitamins and trace elements, it helps maintain healthy joint and disc function.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/#primaryimage\",\"url\":\"https:\\\/\\\/nugenis.eu\\\/wp-content\\\/uploads\\\/2020\\\/10\\\/ecp-v02.jpg\",\"contentUrl\":\"https:\\\/\\\/nugenis.eu\\\/wp-content\\\/uploads\\\/2020\\\/10\\\/ecp-v02.jpg\",\"width\":1000,\"height\":1000},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/cartilage-protector\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/nugenis.eu\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cartilage Protector\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/nugenis.eu\\\/#website\",\"url\":\"https:\\\/\\\/nugenis.eu\\\/\",\"name\":\"NUGENIS\",\"description\":\"Gesund sein und gesund bleiben!\",\"publisher\":{\"@id\":\"https:\\\/\\\/nugenis.eu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/nugenis.eu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/nugenis.eu\\\/#organization\",\"name\":\"NUGENIS GmbH\",\"url\":\"https:\\\/\\\/nugenis.eu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/nugenis.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/nugenis.eu\\\/wp-content\\\/uploads\\\/2016\\\/08\\\/favicon_.png\",\"contentUrl\":\"https:\\\/\\\/nugenis.eu\\\/wp-content\\\/uploads\\\/2016\\\/08\\\/favicon_.png\",\"width\":500,\"height\":500,\"caption\":\"NUGENIS GmbH\"},\"image\":{\"@id\":\"https:\\\/\\\/nugenis.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/nugenis\\\/?fref=ts\"]}]}<\/script>\n<meta property=\"product:price:amount\" content=\"24.90\" \/>\n<meta property=\"product:price:currency\" content=\"EUR\" \/>\n<meta property=\"og:availability\" content=\"instock\" \/>\n<meta property=\"product:availability\" content=\"instock\" \/>\n<meta property=\"product:retailer_item_id\" content=\"62\" \/>\n<meta property=\"product:condition\" content=\"new\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Cartilage Protector - NUGENIS","description":"ECP\u00ae - Epigenetic Cartilage Protector is a cutting-edge dietary supplement based on applied epigenetics, designed to protect and regenerate joint cartilage and discs. Featuring the biologically active form of S-Adenosyl-L-Methionine (SAM-e), this formula supports inflammation reduction, pain relief, and cellular regeneration, especially for osteoarthritis. Enriched with vitamins and trace elements, it helps maintain healthy joint and disc function.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nugenis.eu\/en\/cartilage-protector\/","og_locale":"en_US","og_type":"article","og_title":"Cartilage Protector","og_url":"https:\/\/nugenis.eu\/en\/cartilage-protector\/","og_site_name":"NUGENIS","article_publisher":"https:\/\/www.facebook.com\/nugenis\/?fref=ts","article_modified_time":"2025-02-13T14:01:12+00:00","og_image":[{"width":1000,"height":1000,"url":"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ecp-v02.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"17 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/nugenis.eu\/en\/cartilage-protector\/","url":"https:\/\/nugenis.eu\/en\/cartilage-protector\/","name":"Cartilage Protector - NUGENIS","isPartOf":{"@id":"https:\/\/nugenis.eu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/nugenis.eu\/en\/cartilage-protector\/#primaryimage"},"image":{"@id":"https:\/\/nugenis.eu\/en\/cartilage-protector\/#primaryimage"},"thumbnailUrl":"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ecp-v02.jpg","datePublished":"2016-11-16T11:22:56+00:00","dateModified":"2025-02-13T14:01:12+00:00","description":"ECP\u00ae - Epigenetic Cartilage Protector is a cutting-edge dietary supplement based on applied epigenetics, designed to protect and regenerate joint cartilage and discs. Featuring the biologically active form of S-Adenosyl-L-Methionine (SAM-e), this formula supports inflammation reduction, pain relief, and cellular regeneration, especially for osteoarthritis. Enriched with vitamins and trace elements, it helps maintain healthy joint and disc function.","breadcrumb":{"@id":"https:\/\/nugenis.eu\/en\/cartilage-protector\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nugenis.eu\/en\/cartilage-protector\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nugenis.eu\/en\/cartilage-protector\/#primaryimage","url":"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ecp-v02.jpg","contentUrl":"https:\/\/nugenis.eu\/wp-content\/uploads\/2020\/10\/ecp-v02.jpg","width":1000,"height":1000},{"@type":"BreadcrumbList","@id":"https:\/\/nugenis.eu\/en\/cartilage-protector\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/nugenis.eu\/en\/"},{"@type":"ListItem","position":2,"name":"Cartilage Protector"}]},{"@type":"WebSite","@id":"https:\/\/nugenis.eu\/#website","url":"https:\/\/nugenis.eu\/","name":"NUGENIS","description":"Gesund sein und gesund bleiben!","publisher":{"@id":"https:\/\/nugenis.eu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nugenis.eu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/nugenis.eu\/#organization","name":"NUGENIS GmbH","url":"https:\/\/nugenis.eu\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nugenis.eu\/#\/schema\/logo\/image\/","url":"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/favicon_.png","contentUrl":"https:\/\/nugenis.eu\/wp-content\/uploads\/2016\/08\/favicon_.png","width":500,"height":500,"caption":"NUGENIS GmbH"},"image":{"@id":"https:\/\/nugenis.eu\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/nugenis\/?fref=ts"]}]},"product_price_amount":"24.90","product_price_currency":"EUR","og_availability":"instock","product_availability":"instock","product_retailer_item_id":"62","product_condition":"new"},"_links":{"self":[{"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/pages\/519","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/comments?post=519"}],"version-history":[{"count":8,"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/pages\/519\/revisions"}],"predecessor-version":[{"id":7125,"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/pages\/519\/revisions\/7125"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/media\/4594"}],"wp:attachment":[{"href":"https:\/\/nugenis.eu\/en\/wp-json\/wp\/v2\/media?parent=519"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}