NUGENIS โ DR EDUARD RAPPOLD, MSc
Immersed in Alzheimer-Research
Dr. med. Eduard Rappold, MSc
Scientist and medical practitioner
NUGENISEduard Rappold is a physician, researcher, and author specializing in epigenetics, prevention, and healthy aging.
His work bridges scientific insights from Alzheimerโs research, mitochondrial biology, and stress regulation with practical strategies to support long-term health.
As the founder of NUGENIS, his mission is clear:
to understand biological regulationโand to actively support it.
His approach is based on a central insight: health is not a matter of chance, but the result of modifiable processes at the cellular level.
At the core are epigenetic mechanisms that can be influenced by nutrition, lifestyle, and environmental factors.
Through Epigenetik.at, he provides a platform that translates complex science into clear, actionable knowledgeโoffering new perspectives on health, disease, and prevention.
Selected publications
Therapeutics That Can Potentially Replicate or Augment the Anti-Aging Effects of Physical Exercise
Adriana De Sousa Lages, Valentim Lopes, Joรฃo Horta, Joรฃo Espregueira-Mendes, Renato Andrade and Alexandre Rebelo-Marques [Read]
Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimerโs disease mouse model
Kiara Freitag, Nele Sterczyk, Sarah Wendlinger, Benedikt Obermayer, Julia Schulz, Vadim Farztdinov, Michael Mรผlleder, Markus Ralser, Judith Houtman, Lara Fleck, Caroline Braeuning, Roberto Sansevrin, Christian Hoffmann, Dragomir Milovanovic, Stephan J. Sigrist, Thomas Conrad, Dieter Beule, Frank L. Heppner, and Marina Jendrach [Read]
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression
Jin Zhou, Jeremy Pang, Madhulika Tripathi, Jia Pei H,Anissa Anindya Widjaja, Shamini Guna Shekeran, Stuart Alexander Cook, Ayako Suzuki, Anna Mae Diehl ,Enrico Petretto , Brijesh Kumar Singh1 & Paul Michael Yen [Read]
Gender-related increase of tropomyosin-1 abundance in platelets of Alzheimerโs disease and mild cognitive impairment patients
Reumiller, CM., Schmidt, GJ., Dharami, I., Umlauf, E., Rappold, E., Zellner, M.
Journal of Proteomics (2017) (epub ahead of print) [Read]
Careful neuropsychological testing reveals a novel genetic marker, GSTO1*C, linked to the pre-stage of Alzheimerโs disease
Umlauf,E., Rappold, E., Schiller, B., Fuchs, P., Rainer, M., Wolf, B., Zellner, M.
Oncotarget 7 (26) (2016) [Read]
A platelet protein biochip rapidly detects an Alzheimerโs disease-specific phenotype
Veitinger, M., Oehler, R., Umlauf, E., Baumgartner, R., Schmidt, G., Gerner, Ch., Babeluk, R., Attems, J., Mituloviฤ, G., Rappold, E., Lamont, J., Zellner, M.
Acta Neuropathologica 128(5) (2014) [Read]
Impact of Ademetionine Disulfate Tosylate /Vitamin B12 therapy on cognition in Alzheimerโs Disease and related biomarkers
Rappold E.
Master-These an der Donau-Universitรคt Krems (2014)
Identification and validation of platelet low biological variation proteins, superior to GAPDH, actin and tubulin, as tools in clinical proteomics
Baumgartner, R., Umlauf, E., Veitinger, M., Guterres, S., Rappold, E., Babeluk, R., Mituloviฤ, G., Oehler, R., Zellner, M.
Journal of proteomics 94C:540-551 (2013) [Read]
Comparative platelet proteome analysis reveals an increase of monoamine oxidase-B protein expression in Alzheimerโs disease but not in non-demented Parkinsonโs disease patients
Zellner; M. , Baureder, M., Rappold, E., Bugert, P., Kotzailias, N., Babeluk, R., Baumgartner, R., Attems, J., Gerner, Ch., Jellinger, K., Roth, E., Oehler, R., Umlauf, E.ยท
Journal of proteomics 75(7):2080-92 (2012) [Read]
Langzeiternรคhrungstherapie einer hochbetagten Seniorin. Positive Effekte durch die Gabe von Sondennahrung auf Basis von Lebensmittel
Rappold, E. ยท
focus neurogeriatrie 3(1):16-20 (2009)
Biological Variation of the Platelet Proteome in the Elderly Population and Its Implication for Biomarker Research
Winkler, W., Zellner, M., Diestinger, M., Babeluk, R., Marchetti, M., Goll, A., Zehetmayer, S., Bauer, P., Rappold, E., Miller, I., Roth, E., Allmaier, G., Oehler, R. ยท
Molecular & Cellular Proteomics 7(1):193-203 (2008) [Read]
Aspekte der kรผnstlichen Ernรคhrung bei demenzkranken Patienten in der Geriatrie
Rappold, E., Kratochvila, H. G.
Ethik in der Medizin 16(3):253-264 (2004)
Downregulation of carnitine acyltransferases and organic cation transporter OCTN2 in mononuclear cells in healthy elderly and patients with myelodysplastic syndromes
Karlic, H., Lohninger, G., Laschan, C., Lapin, A., Bรถhmer, F., Huemer, M., Guthann, E., Rappold, E., Pfeilstรถcker, M.
Journal of Molecular Medicine 81(7):435-42 (2003) [Read]
Treatment of polymorphous light eruption with nicotinamide: a pilot study
Neumann, R., Rappold, E., Pohl-Markl, H.
British Journal of Dermatology 115(1):77-80 (1986) [Read]
Innovation
In 2015, NUGENIS was a awarded the gold medal at the most important international trade fair for โIdeas, Invention and New Productsโ, iENA , for EBPยฎ Epigenetic Brain Protector as an outstanding contribution to the protection of our brain cells.