Spermidine 3 mg per Capsule

Natural Wheat Germ Extract

with High Spermidine Content

60 Capsules

 

Discover the various health benefits of spermidine:

  • Supports cellular health alongside S-Adenosyl-L-Methionine (SAM-e).
  • Induces autophagy, aiding cellular rejuvenation.
  • Suppresses oxidative cell stress and protects all body cells and organ systems.
  • Exhibits anti-inflammatory properties, aiding in acute and chronic inflammation.
  • Enhances immune function.
  • Protects brain cells, supporting improved cognition.

Fig. Bivariate correlation between serum spermidine (Spd) levels and mini-mental state examination (MMSE). Kendall rank correlation coefficient tau‑b between spermidine and mini-mental state examination (MMSE) is 0.153 (p = 0.025)

Pekar, T., Wendzel, A., Flak, W. et al. Spermidine in dementia. Wien Klin Wochenschr 132, 42–46 (2020).

  • Promotes mitochondrial health.
  • Boosts overall protein synthesis, vital for cellular repair and function.
  • Offers cardioprotective effects, stabilizing mitochondrial function and reducing cardiovascular mortality.
  • Influences sleep patterns by regulating circadian rhythms.
  • Provides protective and regenerative effects on joint cartilage and intervertebral discs.
  • Improves the appearance and functional properties of skin, hair, and nails.
  • Lowers insulin levels and reduces the risk of diabetes and obesity.

 

The de novo biosynthesis of spermidine in the organism requires the presence of S-adenosylmethionine (Ademetionine, SAM-e). Putrescine is converted to spermidine by spermidine synthase through the addition of a propylamine group derived from the decarboxylation of S-adenosylmethionine (Amino-Propylation in the carbon-1 cycle).

 

SPERMIDINE DEFICIENCY

Tissue spermidine concentrations and plasma spermidine levels decrease as early adulthood approaches.

The blood spermidine level has already decreased by one-third compared to youthful levels in early adulthood. By the age of 80, two-thirds of the body’s physiological spermidine content is missing, and spermidine becomes essential for substitution.

Fig. Bivariate correlation analyses in men and women show a highly significant negative correlation between serum spermidine levels and age (p <0.001) (Pekar T, 2020).

 

Recommended Dosage: Take 2 capsules daily with 200 ml of liquid during a meal. Do not exceed the recommended daily dose.

Storage Instructions: Store below 25°C, in a dry place protected from light. Keep the container tightly closed after use. Keep out of reach of small children.

Important Notes: Not suitable for individuals under 18 years, pregnant or nursing women. Food supplements are not a substitute for a varied and balanced diet, and a healthy lifestyle.

Ingredients: Wheat Germ Extract, Bulking Agent: Microcrystalline Cellulose, Maltodextrin, Coating Agent: Hydroxypropyl Methylcellulose.

Contents per Daily Dose (2 Capsules):

  • Wheat Germ Extract: 600 mg
  • Spermidine: 6 mg

Content: 60 vegan capsules 100% plant-based, GMO-free, kosher, and halal, free from gluten, lactose and fructose.

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Spermidine 3 mg per Capsule

Natural Wheat Germ Extract with high Spermidine content

60 Capsules

 

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